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MGH Faculty Development Podcast

Massachusetts General Hospital (MGH)
Faculty Development Podcast

Mar 16, 2023

“Novel role of chemokines in the ovulatory cascade and their potential application for nonhormonal contraceptive development”

The Anne Klibanski Visiting Lecture Series was created to support and advance the careers of women. These lectures offer the opportunity for women faculty from outside institutions that have hosted Anne Klibanski Scholars to present on their expertise, either alone or in tandem with an Anne Klibanski Scholar.

PresenterMarina Cinthia Peluffo, PhD, Independent Scientist, CONICET, División de Endocrinología, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina

Learning Objectives:
Upon completion of this activity, participants were able to:

  • Describe the periovulatory events and the increasing evidence for the role of chemokines in regulating these crucial events in different species
  • Assess our laboratory evidence regarding the chemokine receptor CCR2 and its chemokine ligands in the ovarian follicles and cumulus-oocyte complex (COC) in the rhesus monkeys and domestic cats
  • Analyze the direct effect of triggering or inhibiting the CCR2 receptor within the COC using a feline model in vitro
  • Evaluate the interaction between the CCR2 and epidermal growth factor receptor (EGFR, a crucial intermediate in the ovulatory cascade) systems within the feline COC
  • Review and discuss the overall course of this research

Click here to watch webinar.